Trey Ideker is an expert in computational biology and genomics. His work focuses on technology to map the genetic networks inside cancer cells and to use this information in patient diagnosis and therapy. Although genome sequencing has provided a new window on the DNA mutations that cause cancer, these data have proven difficult to interpret as two patients rarely share the same mutations. Ideker recently introduced a computational approach called network-based stratification, which groups patients with mutations in the same genetic networks. This approach has identified new subtypes for ovarian and head and neck cancers. Ideker is a founder of popular software tools and databases such as Cytoscape, a network analysis suite that is downloaded more than 30,000 times a month. See idekerlab.ucsd.edu/ and cytoscape.org for more information.
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